Abstract
Yohimbe plant Pausinystalia johimbe (K. Schum.) Pierre ex Beille is an evergreen tree that grows in West and Central Africa. Yohimbine and a group of other indole alkaloids, found in the bark of yohimbe, have traditionally been used for their aphrodisiac effects. An UHPLC-UV-MS/MS method was developed for quantitative determination of caffeine, yohimbic acid, corynanthine, yohimbine and rauwolscine from yohimbe supplement products as well as yohimbe plant samples. Caffeine is not found in yohimbe plant, and yohimbine ranged from 0.56% – 1.8% (w/w) in 12 samples of yohimbe plants. All 56 supplement products available at mainstream retail stores and labeled as containing yohimbe were analyzed. Results from 12 plant samples and 56 supplement samples will be presented. In short, high dosages of yohimbine alkaloid were detected without the additional alkaloids that would be expected from yohimbe plant extracts. Significant dosages of caffeine were also found in many supplements.
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