Abstract
Determination of Bacterial Profile and Spectrum of Antimicrobial Drug Resistance in Pediatric Wound Infections
Highlights
Human skin is a first protective obstacle that inhibits microbial infections by creating an effectual barrier, leaving the tissue underneath intact[1]
The majority of Gram-negative bacteria were resistant to cephalosporins and aminoglycosides, while lesser resistance observed against carbapenems, piperacillin-tazobactam, and cefoperazone-sulbactam
Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Streptococcus pyogenes, Proteus, other Streptococci, and Enterococci are common bacterial pathogens associated with wound infection[8]
Summary
Human skin is a first protective obstacle that inhibits microbial infections by creating an effectual barrier, leaving the tissue underneath intact[1]. Most of the bacterial species have a weak potential for infections because of the intact human skin[2]. Child injuries are a common public health concern and usually occur when the child has a burn injury, falls from the height, or a road accident. These multiple injuries lead to the formation of wounds that bring the patients into health care facilities[3]. Wound infection is triggered by weak skin integrity, type of organism, virulence, nature of the operation, antibiotics, and mechanism of host defense. The bacterial pathogens, chronic inflammation, and unbalanced cellular defense mechanisms characterize infected wounds[5]. The bacterial wound infection can be polymicrobial with the co-existence of multiple pathogenic bacteria in the same wound[9]
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