Abstract
Laetiporus sulphureus (Bull.) Murrill belongs to the family of Polyporaceae which appears strident orange or sulfur yellow colouration, commonly known as chicken of the wood, which is found in hardwood and is cautiously consumed by humans. Recent research revealed that it is a prominent source of bioactive compounds having potential sources for antioxidants and other pharma-active components. Thus, the present objectives are to determine and to choose the potential polar solvent for extract preparation and then to validate the potency of the antioxidant and antidiabetic properties. The current studies employed various polar solvents for extract preparation. The experimentation recorded that the methanol solvent had shown a maximum yield of extracts (11.05±0.05 (g /100 dry weights). The obtained extracts were tested and significant results were obtained for antioxidant and antidiabetic assays. It has been recorded as a decrease dose with increasing order of concentration of extracts with a total of 50% inhibition (IC50). The studies suggested that L. sulphureus has therapeutic and nutritional values, which will be used for various human ailments and provide alternative sources for the pharmaceutical industry instead of chemically synthesized materials.
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