Abstract
The high use of antibiotics causes the increasing trend of microbial resistance, followed by the limitation of treatment options, the complexity of the treatment, and the increase in the cost of the healthcare system. In this study, we examined antibiotic resistance of E. coli isolated from urine culture samples in Shahid Sadoughi Hospital, Yazd. This cross-sectional study was conducted on urine cultures related to patients hospitalized in different wards of Shahid Sadoughi Hospital in Yazd in 2021. Antibiotic resistance to E. coli isolates was investigated in 395 cultures, and the data was analyzed using SPSS software (version 26). The highest antibiotic resistance of E. coli was to ampicillin. Resistance to gentamicin was the highest in the surgery ward and the lowest resistance was observed in the women's ward. Also, the resistance to cefepime was the highest in the surgery ward and the lowest resistance rate was related to the emergency ward. The results of the present study showed the high antibiotic resistance of Ecoli isolates in hospitalized patients with urinary tract infection, especially in the population of men and elderly people.
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