Determination of antibacterial residues in raw cattle beef in some selective areas of Mymensingh District during Eid-ul-Adha

M Comruzzaman,M M Alam,N Hassan,A K M H Kabir,A Nahar

doi:10.33109/bjvmjd2020rm4

Abstract

Background: Antibiotic residue in foods of animal origin is a growing public health concern in recent time. Indiscriminate use of antibacterials in food animal production and ignoring proper withdrawal period may lead to drug residue in milk, beef and eggs. The present study was conducted to detect antibacterial residues in raw cattle beef samples. Methods: One hundred cattle beef samples were collected from four Upazillas of Mymensingh named Gofargaon, Fulpur, Dhobaura and Bhaluka, Bangladesh during the period of Eid-ul-adha in 2018. The residue of two most commonly used antibacterials named oxytetracycline (OTC) and sulphadimidin (SDI) were quantified by using High Performance Liquid Chromatography (HPLC). Results The mean concentration of OTC and SDI residues in raw beef samples were 0.145 µg/ml and 0.094 µg/ml and the concentration ranged from 0.104-0.435 µg/ml and 0.083-0.357 µg/ml, respectively. About 59% and 43% beef samples contained some levels of OTC and SDI residue, respectively. Importantly, 19% and 12% beef samples exceeded maximum residue limit (MRL) for OTC and SDI, respectively. Conclusions: The results indicate that drug residue is common in raw beef samples and a good proportion of beef samples exceeded MRL. Farmer’s education to ensure rational use of antibacterials and to follow withdrawal period may help control this public health hazards in Bangladesh context.

Highlights

Antibiotic resistance (AMR) has gained a global health concern
The results indicate that drug residue is common in raw beef samples and a good proportion of beef samples exceeded maximum residue limit (MRL)
The most common causes for the presence of antibiotic residues in food of animal origin are violation of withdrawal periods, overdosing of antibiotics and use of antibiotics banned for treatment of economic animals

Summary

Introduction

Antibiotic resistance (AMR) has gained a global health concern. A recent scientific review indicates that if no solutions are found, infections caused by AMR pathogens will lead to around 700,000 deaths in a year and are predicted to cause 10 million deaths annually by 2050 (WHO, 2016). Extensive use of antimicrobials as therapy and prevention of human and animal diseases as well as antimicrobial growth promoters (AGPs) in food animals and subsequent release of these drug residues through milk, beef and egg is a leading cause of development of antibiotic resistance in the human body (Woolhouse et al, 2015). The use of this compound may result in residues in animal derived food products, especially if withdrawal times are not observed. These residues may pose a health threat to consumers, depending on the type of food and the amount of residue present. Indiscriminate use of antibacterials in food animal production and ignoring proper withdrawal period may lead to drug residue in milk, beef and eggs. The present study was conducted to detect and quantify antibacterial residues in raw cattle beef samples

Methods

Results

Discussion

Conclusion