Abstract

Alkannin and Shikonin (A/S) derivatives are optical antipodes of plant origin with a verified wide spectrum of antimicrobial, wound healing, anti-inflammatory and antioxidant activity. Although the aforementioned antipodes were originally introduced as wound healing agents, recent studies on cancer chemotherapy revealed that A/S also exhibit antitumor activity. A/S have been found in roots of several Boraginaceous species[1–3]. Determination of A/S, their esters and the total A/S content in Boraginaceous roots of different origin was reported in several papers[4–7].

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