Abstract
Abstract A method has been developed for determining the absolute configurations of acyclic tertiary alcohols using their 2NMA [methoxy-(2-naphthyl)acetic acid] esters. The 1H NMR spectra of (R)- and (S)-2NMA esters of model compounds were measured, and Δδ values (δR-ester − δS-ester) were calculated. The absolute configuration for tertiary hydroxy group is determined based on the sign of Δδ values like that for secondary hydroxy group.
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