Determinants of Treatment Delay in Drug-Resistant Tuberculosis Patients in Banten Province in 2020

Abstract

Indonesia is currently ranked 2nd with the most tuberculosis cases in the world, after India and China. is ranked 2nd with the most tuberculosis sufferers in the world, after India and China.
 Tuberculosis control in Indonesia faces many challenges, one of which is the increase in patients
 with drug-resistant tuberculosis (DR TB). In 2019, the number of tuberculosis sufferers in Indonesia
 reached 543,874 cases, with drug-resistant tuberculosis cases reaching 11,463 (2.1%). Banten is
 one of the provinces with the highest number of Tuberculosis sufferers in Java, which is 223 people
 per 100,000 population, with a national TB rate of 203 people per 100,000 population, of which
 only 58.3% take medication regularly. This study aims to determine the determinants of treatment
 delay in drug-resistant tuberculosis patients in Banten province in 2020. The study design was a
 retrospective cohort. The sampling technique was a total sampling of the list of DR TB cases at
 South Tangerang city General Hospital and dr. Drajat Prawiranegara Serang. Secondary data
 search was carried out on the TB Information System (SITB) and patient medical records. The study
 population was 114 respondents, obtained 90 respondents who fit the inclusion and exclusion
 criteria. Univariate, bivariate analysis with chi-square test and multivariate with logistic regression
 statistical test were performed to obtain a fit final model. The results of the bivariate analysis
 showed a significant relationship between age (p=0.030) and employment status (p=0.003). The
 final multivariate model, showing employment status with delayed treatment (p = 0.008), with OR
 18,788 (95% CI: 2,122 – 166.329), meaning that respondents who have jobs have 18.8 times risk for
 late treatment compared to respondents who do not have jobs after being controlled by variables
 of age, gender, history of TB, and education level. The researcher concludes that the determinants
 of delay in treatment of DR TB patients in Banten province in 2020 are employment status and age.
 It is recommended that the Banten Provincial Health Office can coordinate cross sectors, to ensure the treatment of DR TB patients until they are cured.
 Keywords: epidemiology, tuberculosis, drug-resistant