Abstract
Aim. To determine the variability of serum aldosterone in patients with stable coronary artery disease in relation to arterial hypertension status, age, and gender. Materials and Methods. We recruited 176 consecutive patients with stable coronary artery disease and evaluated serum aldosterone by enzyme-linked immunosorbent assay, further comparing its levels with regards to age, gender, and presence of arterial hypertension. Results. Average serum aldosterone in patients with stable coronary artery disease was similar in Kemerovo Region and those reported in the literature. Age ≥ 60 years, female gender, and the presence of arterial hypertension were among the serum aldosterone determinants Conclusions. Females ≥ 60 years of age with a medical history of arterial hypertension have increased serum aldosterone.
Highlights
Average serum aldosterone in patients with stable coronary artery disease was similar in Kemerovo Region and those reported in the literature
Age ≥ 60 years, female gender, and the presence of arterial hypertension were among the serum aldosterone determinants
Суммируя все вышеперечисленные выводы, мы своим исследованием подтверждаем ранее полученные данные о модулирующем эффекте пола, возраста и артериальной гипертонии в анамнезе на содержание сывороточного альдостерона у больных ишемической болезнью сердца (ИБС)
Summary
Age ≥ 60 years, female gender, and the presence of arterial hypertension were among the serum aldosterone determinants Females ≥ 60 years of age with a medical history of arterial hypertension have increased serum aldosterone. Однако опубликованных данных об особенностях содержания альдостерона в сыворотке крови больных ИБС в климатических и экологических условиях Западной Сибири нами обнаружено не было.
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