Determinants of right heart size and function in repaired Tetralogy of Fallot

Abstract

Results RV EDV was positively associated with pulmonary regurgitant (PR) volume (b 0.59, p < 1e), tricuspid regurgitant (TR) volume (b 0.24, p < 1e), body surface area (b 0.08, p < 1e), and age (b 0.20, p < 1e). Significant residual outflow tract stenosis (b -0.10, p = 0.01), branch pulmonary artery stenosis (b -0.09, p = 0.02) and RV EF (b -0.38, p < 1e) were negatively associated with RV EDV (Model, R = 0.81). Initial palliation with a Blalock-Taussig Shunt (b -0.234, p = 0.0001) was associated with lower RV EF. TR volume was associated with higher RV EF (b -0.13, p = 0.03), (Model, R = 0.26); residual outflow tract obstruction was not associated with RV EF. RV ESV had similar associations to RV EDV, except residual outflow tract obstruction and branch PA stenosis were not associated, and RVEF was the most influential covariate (Model, R = 0.83).