Abstract
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Highlights
Hereditary factors account for about 80% of peak bone mass (PBM) variance
Increasing peak bone mass (PBM) and slowing bone loss are generally accepted as preventive measures against osteoporotic fractures later in life
There was a significant interaction between calcium intake and exercise on Bone mineral density (BMD) accretion rates in children < 11 years of age
Summary
Hereditary factors account for about 80% of PBM variance. About 20% is due to environmental factors which can be modified favourably to increase PBM. Determinants of peak bone mass and bone mineralization rates in 470 healthy children, adolescents and young adults: A prospective study Increasing peak bone mass (PBM) and slowing bone loss are generally accepted as preventive measures against osteoporotic fractures later in life. As osteoporosis treatment do not restore bone mass and bone architecture, increasing PBM or preventing bone loss leave the best options of disease handling.
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