Determinants of antimicrobial resistance in a contemporary obstetrical cohort

Abstract

Intraamniotic infection (IAI) causes significant maternal and neonatal morbidity. Antimicrobial resistance is increasing among obstetrical pathogens but studies examining contemporary bacterial isolates and their associated antimicrobial drug resistance patterns are lacking. Guidelines on IAI treatment suggest antibiotic choice should be based on local antimicrobial susceptibility but obstetric bacterial isolates have different antimicrobial resistance patterns compared to medical or surgical patients and it is difficult to ascertain the appropriate antibiotics.