DETERMINANTS INFLUENCING LENGTH OF ICU STAY IN RENAL TRANSPLANT RECIPIENTS UNDERGOING GENERAL ANAESTHESIA

Abstract

Background: In this study, we wantedto evaluate the duration of intensive care unit (ICU) stay in renal transplant recipients and identify the perioperative factors affecting the duration of ICU stay. Materials And Methods: This was a hospital basedprospective cohort study conducted among 76 patients who presented with renal transplantationto the Department ofAnaesthesiology and Intensive Care Unit, Max Super Speciality Hospital, Mohali of Punjab State, from May 2018 toApril 2019after obtaining clearance from Institutional Ethics Committee and written informed consent from the study participants. Results: Longer ICU stay was associated with pleural effusion and left ventricular hypokinesia(p value <0.05). No significant association was found between other clinical conditions and duration of ICU stay.Longer ICU stay was associated if duration of dialysis is longer and thrice a week dialysis. This was statistically significant (p value <0.05).Higher mean serum lactate levels were associated with longer ICU stay (p value <0.05).Longer ICU stay was found in those who had lower mean arterial pressure, higher systolic blood pressure and lower urine output. This was found to be statistically significant. Longer ICU stay was associated with low blood pH, higher serum lactate and lower urine output during post-operative period. This was found to be significant Conclusion:There were certain factors which affected the duration of ICU stay – Older age, higher ASA grades, longer duration of dialysis, and higher frequency of dialysis.Among the perioperative parameters- preoperative mean serum lactate levels, intraoperative lower mean arterial pressure, lower systolic blood pressure and lower urine output, post-operative low blood pH, higher serum lactate and lower urine output were associated with longer duration of ICU stay.