Abstract

Mammalian cell surfaces are covered with a glycocalyx capped with sialic acids (Sias). Human Sias consist of N-acetylneuraminic acids (Neu5Ac) as our species lost the capacity to make the other mammalian Sia – Neu5Gc. Dietary intake of red meat/dairy can incorporate Neu5Gc into human tissues, and humans have circulating antibodies (Ab) against this xenoglycan. This study aims to evaluate the presence of Neu5Gc on sperm and anti-Neu5Gc Ab in seminal fluid (SF) samples.

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