Abstract
Abstract Metabolites of 2,4,6-trinitrotoluene (TNT) were found in the urine of rats and in the blood of rabbits fed with TNT, in the urine of rats exposed to TNT by skin absorption, and in the urine of TNT munition workers. Urine and blood extracts were analyzed by liquid-chromatography/mass spectrometry (LC/MS), The metabolites found included untransformed TNT, 2-amino-4,6-dinitrotoluene (2-A), 4-amino-2,6-dinitrotoluene (4-A), 2,4-diamino-6-nitro-toluene (2-4-DA) and 2,6-diamino-4-nitrotoluene (2,6-DA).
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