Detection of the scrapie agent in tissues of normal mice and in tumours of tumour-bearing but otherwise normal mice.

Abstract

SCRAPIE has been reported in some goats inoculated intracerebrally with suspensions of tissues from some normal goats1,2, and a summary3 of these and other observations made during a 9 yr period recorded five cases of scrapie among seventy-seven goats inoculated with four of twenty-one different normal goat brains, and in one of three goats inoculated with normal goat pancreas. As far as we know, the only other similar record in the literature is of the occurrence of scrapie in four of forty-four sheep inoculated with normal sheep brain4.