Abstract
Objective To study the deletion of the p53 gene in primary lung cancer and it's clinical significance.Methods Fourty-one surgical samples from patients with primary lung cancer were examined for p53 gene deletion by Dual-FISH technique in 2005 to 2008.Results p53 gene deletion was related to differentiation,age of onset (OR=18.775,95%CI2.437-144.636;OR=0.077,95%CI 0.007-0.874;P 0.05).Conclusions Detections of p53 gene deletion was related to differentiation of pathological grades,which might be a useful index in evaluating patients'prognosis. Key words: Dual-FISH; Lung cancer; p53 gene; Genetics
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
