Abstract
We analyzed the possibility to detect microcalcifications using a novel ultrasound diagnostic mode based on advanced analysis of the color Doppler twinkling artifact. The special mode was tested with two phantoms: a commercially available polyurethane mammographic breast phantom with dense inclusions simulating microcalcifications and a phantom developed in our laboratory and containing chemically grown CaSO4 microcrystals less than 200 μm in size. The mineral inclusions in the first phantom were visible in B-mode and correctly detected with the novel mode. The presence of inclusions in the second phantom was not obvious when imaged in B-mode; however, it was reliably detected with the special mode. The special mode used two colors to distinguish between the physical processes behind the color Doppler twinkling artifact — elastic vibration and microcavitation. This research demonstrated the applicability and usefulness of the special diagnostic mode for the detection of microcalcifications in phantoms.
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