Abstract
This study was done to evaluate a new technique to determine the presence of methamphetamine in the hair using nano bentonite-based adsorbent as the filler of extraction column. The state of the art of this study was based on the presence of silica in the nano bentonite that was assumed can interact with methamphetamine. The hair used was treated using methanol to extract the presence of methamphetamine, then it was continued by sonicating the hair sample. Qualitative analysis using Marquish reagent was performed to confirm the presence of methamphetamine in the isolate.The hair sample that has been taken in a different period confirmed that this current developing method can be used to analyzed methamphetamine. This method has an average recovery percentage by 104%. This result was also supported by the precision, linearity, LOD and LOQ, i.e. 0.0775; 0.968; 0.00000256 and 0.000000775, respectively.
Highlights
Methamphetamine has been recognized as a therapeutic drug, but nowadays it has been used for illegal purposes[1]
This is an advantage of hair sample than other biological matrices, for example, urine, the methamphetamine only can be found in urine for a short time, normally for hours[7,8,9]
The experimental result proves that the proposed method is effective to detect methamphetamine in human hair
Summary
Methamphetamine has been recognized as a therapeutic drug, but nowadays it has been used for illegal purposes[1]. Every biological sample has different properties and different way to handle for the determination of methamphetamine, it provides valuable information, i.e., exposure time From all of those biological matrixes, hair is the best matrix for methamphetamine analysis. A hair sample can be used to analyze methamphetamine without giving us a worry that the methamphetamine will be lost, because hair is just like storage that can keep the drug longer than any kind of biological matrix and the information of how long the suspect uses methamphetamine can be known from every inch of their hair This is an advantage of hair sample than other biological matrices, for example, urine, the methamphetamine only can be found in urine for a short time, normally for hours[7,8,9]
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