Abstract
A hollow-core metal-cladding waveguide (HCMW) optofluidic resonator that works based on a free-space coupling technique is designed. An HCMW can excite ultra-high-order modes (UOMs) at the coupled angle, which can be used as an optofluidic resonator to detect alterations of the epidermal growth factor receptor (EGFR) concentration. Theoretical analysis shows that the UOMs excited in the HCMW have a highly sensitive response to the refractive index (RI) variation of the guiding layer. An EGFR solution with a 0.2 ng/mL alteration is detected, and the RI variation caused by the concentration alteration is about 2.5×10−3.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.