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Abstract
To determine whether Lassa virus was circulating in southern Mali, we tested samples from small mammals from 3 villages, including Soromba, where in 2009 a British citizen probably contracted a lethal Lassa virus infection. We report the isolation and genetic characterization of Lassa virus from an area previously unknown for Lassa fever.
Highlights
To determine whether Lassa virus was circulating in southern Mali, we tested samples from small mammals from 3 villages, including Soromba, where in 2009 a British citizen probably contracted a lethal Lassa virus infection
We provide evidence that LASV is circulating in M. natalensis in southern Mali, thereby expanding the geographic distribution of LASV in West Africa and posing a risk to humans in an area previously unknown for Lassa fever
This study demonstrates that M. natalensis rats in Mali carry a genetically unique strain of LASV
Summary
To determine whether Lassa virus was circulating in southern Mali, we tested samples from small mammals from 3 villages, including Soromba, where in 2009 a British citizen probably contracted a lethal Lassa virus infection. The patient had no travel history to any LASV-endemic region, which suggests that he contracted the infection in Mali, most likely while working in the village of Soromba (Figure 1). We provide evidence that LASV is circulating in M. natalensis in southern Mali, thereby expanding the geographic distribution of LASV in West Africa and posing a risk to humans in an area previously unknown for Lassa fever.
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