Abstract
Influenza A virus infection has rarely been documented to cause viremia. In 28 blood donations in Brazil that were deferred because of postdonation information, we identified influenza A(H3N2) virus RNA in 1 donation using metagenomic analysis. Our finding implies theoretical risk for viremia and transfusion transmission.
Highlights
Influenza A virus infection has rarely been documented to cause viremia
In 28 blood donations in Brazil that were deferred because of postdonation information, we identified influenza A(H3N2) virus RNA in 1 donation using metagenomic analysis
Influenza viremia may be established within 2–3 days before onset of clinical symptoms [2], implying that this virus is hypothetically transmissible by blood transfusion
Summary
In 28 blood donations in Brazil that were deferred because of postdonation information, we identified influenza A(H3N2) virus RNA in 1 donation using metagenomic analysis. Influenza viremia may be established within 2–3 days before onset of clinical symptoms [2], implying that this virus is hypothetically transmissible by blood transfusion. Transmission has never been confirmed, and efforts to detect influenza virus RNA among blood donors have been unsuccessful [3,4,5].
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