Abstract
Helicobacter pylori (HP) DNA was assayed using a newly fabricated voltammetric handheld circuit equipped with an interfaced graphite pencil electrode (PE) sensor. Under optimum analytical parameters, the square-wave (SW) stripping detection range attained was 0.1-0.7 mg/L. A relative standard deviation of 1.68% (RSD, n = 5) was observed at a 3.2 mg/L HP DNA within a 90 s accumulation time. Under these conditions, the analytical detection limit approached 0.07 mg/L. The developed methods can be applied to HP assays of preliminary stage gastric cancer patient tissues.
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