Abstract
Background: The most prevalent single gene disorders in India are hereditary haemoglobin (Hb) abnormalities. Because North East India lacks information on the pattern of hemoglobinopathies and thalassemias, it was thought beneficial to research these conditions using a series of patients sent to a clinical diagnostic laboratory. To study Aimthe spectrum of different haemoglobin variants in patients with Anaemia The study is carried out for Methods: a period of one year from July 2021 to June 2022. A total number of 90 cases of anemia were studied during this period. HPLC was done using BIORAD D-10 machine and the data were analysed. Of the 90 cases, 23 was diagnosed as HbE Results: Trait, 5 as HbE Disease, 8 as β- Thalassaemia Trait, 2 as Sickle Cell Trait, 1 each as HbE- β- Thalassaemia Trait and HbD Punjab, 33 as Iron Deficiency Anaemia and 17 as Anaemia of chronic disease. There is a female preponderance of the haemoglobin variants
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