Abstract
Glaucoma is an asymptomatic neurological disease. It causes damage to optic nerve due to increased fluid pressure within eyes. In the proposed system, cup-to-disc-ratio has been computed considering internal layers of the retina using spectral-domain optical coherence tomography images. In the cupdiameter-calculation process, cup contour has been extracted from inner-limiting-membrane (ILM) layer. The paper introduces a new method to improve the precision of the ILM-layer extraction. It also employs a novel technique to refine contour of an ILM layer. The novel method has outperformed interpolation and Bezier curve fitting in term of outliers' removal and surface refinement. In the disc-diameter-calculation process, the retinal-pigment-epithelium (RPE) layer end points have been used to define disc margin. Prior to RPE-layer extraction, ILM-Layer removal has been done by an innovative strategy to locate and remove ILM-layer. Finally, precise RPE-layer extraction has been done based on the novel thickness-value (TV) estimation method. Furthermore, a new criterion for cup edges determination, based on the mean value of RPE-layer end points, is proposed. The proposed system has shown a clear precedence over its contemporary systems in terms of accuracy and handling of acute cases. Satisfactory results have been obtained when compared with the clinical results.
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