Detection of fungal infection and antibiotic susceptibility test in 458 patients with balanoposthitis

Abstract

Objective To understand the fungal infection and antibiotic susceptibility in patients with balanoposthitis in Zhaoqing.Methods CHROM agar candida,ATB ID32C of France Bio-Merieux Company and Rosco Disk diffusion method were applied to culture and identify candida strains and for yeast susceptibility testing.Results 157 cases(34.3％) were infected by candida in the 458 patients; of which,116 (73.9％) were infected by candida albicans,14 (8.9％) by candida glabrata,12 (7.6％) by candida tropicalis,8 (5.1％) by candida parapsilosis,5 (3.2％) by candida krusei,and 2 (1.3％) by candida guilliermondii.The susceptibility rate of the isolated strains to nystatin and ketoconazole were both more than 90.0％,97.5％ and 93.0％,respectively.The susceptibility rate to fluconazole was 79.6％,while the susceptibility rate to terbinafine was lowest,33.8％.Conclusions Candida infection is the most important pathogenetic factor for balanoposthitis and the main species of pathogenetic yeasts is candida albicans in Zhaoqing area.Candida have a higher drug susceptibility rate to polyene drugs and have different degree of cross resistance to azole drugs.There are differences among the antibiotic sensitivity spectrums of various candida. Key words: Balanoposthitis; Fungi; Candida; Susceptibility test