Abstract
Detection Of Four Dengue Serotypes Suggests Rise In Hyperendemicity In Urban Centers Of Brazil
Highlights
Hyperendemicity was first associated with increased transmission and the emergence of severe dengue in Asia in the 1950s and in the Caribbean in the 1980s [1]
We need to take into account that simultaneous or sequential epidemics with different serotypes are a common risk factor associated with severe cases [1]
To corroborate if hyperendemicity is being established in a populated area in the country, we determined whether one serotype or multiple ones caused the 2013 epidemic in some critical localities in the state of Sao Paulo
Summary
Hyperendemicity was first associated with increased transmission and the emergence of severe dengue in Asia in the 1950s and in the Caribbean in the 1980s [1]. A similar epidemiological pattern of cocirculation in the most highly populated urban areas of Brazil has not been reported so far and is of utmost relevance, since distinct genotypes from the four serotypes have been reported in Brazil. DENV-4 was isolated for the first time in 1982 in a focal epidemic in the northwestern region of the Brazilian Amazon.
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