Abstract
Ninety liver samples of poultry, sheep and cattle, 30 each, were obtained from meat retail markets at Mosul city in Iraq, and were analyzed for enrofloxacin residue by using Enzyme Linked Immunosorbent Assay, ELISA [ Schen Zhen Lvshiynan Biotechnology Co., LTD. (china)]. The study revealed that the range and mean of residual enrofloxacin drug concentration in the examined liver samples of poultry, cattle and sheep were (0.01-10.69) (4.290); (0.03-3.61) (1.750); (0.02-1.32) (1.687) mg/ kg respectively. Also the study revealed that 30 (33.31%) of poultry liver samples tested positive, 8 (8.88%) of cattle samples were positive, and 5 (5.55%) of sheep samples were positive for enrofloxacin. 17 (56.66%) of the poultry samples exceeded the maximum residues limits (MRL), as did 8 (26.61%) of cattle samples, and 5(16.6%) of sheep samples. Our results have shown that the maximum mean enrofloxacin concentration was found in poultry livers (4.290) and the minimum mean was in the ovine liver samples (1.687) while bovine livers were (1.750). The difference between the residue of enrofloxacin of poultry liver samples and that of bovine and ovine liver samples was significant at (P<0.05).
Highlights
Enrofloxacin is one of the third generation members of the fluoroquinolone antibacterial agents
The results of our study revealed that the ranges and means of residual enrofloxacin concentrations in the examined liver samples of poultry, cattle and sheep were (0.01- 10.69; 4.290), (0.03-3.61; 1.750), (0.02-1.32; 1.687) mg/kg respectively (Table 1)
Our results have shown that the maximum mean of enrofloxacin concentration was found in the poultry liver (4.290), the minimum mean was in the sheep liver samples (1.687), while cattle was (1.750)
Summary
Enrofloxacin is one of the third generation members of the fluoroquinolone antibacterial agents. Fluoroquinolones (FQs) are highly effective synthetic antibiotics Their therapeutic mechanism of actions are based on the inhibition of DNA gyrase in gram-negative species and topoisomerase IV in gram-positive species [1,2]. They have been recommended for the treatment of urinary tract and enteric infections in humans. These drugs are normally prescribed for the treatment and prevention of infectious diseases in farm animals It is routinely considered as a protective measure when raising animals under intensive husbandry production methods [3]. They have been used in sub-therapeutic levels as feed additives for promoting and protecting normal growth of meat production livestock [4]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
