Abstract
Arterial wall inflammation destabilizes atherosclerotic plaques and makes them prone to rupture (1) so detection of inflammatory activity may therefore assist discrimination between unstable and stable plaques. Inflammation of the vessel wall prompts transport of excess fluid into the interstitial space and results in the formation of edema (2). Hence, edema located within the vessel wall can be used as a marker for inflammatory activity.
Highlights
Arterial wall inflammation destabilizes atherosclerotic plaques and makes them prone to rupture (1) so detection of inflammatory activity may assist discrimination between unstable and stable plaques
We wished to determine whether edema could be detected in the carotid artery wall by cardiovascular magnetic resonance (CMR) using a T2-weighted shorttau inversion recovery sequence (T2-STIR)
The relative signal intensity and area of enhancement showed a linear correlation with the area of fibrinogen detected on the corresponding histopathology (r=0.80, p
Summary
Arterial wall inflammation destabilizes atherosclerotic plaques and makes them prone to rupture (1) so detection of inflammatory activity may assist discrimination between unstable and stable plaques. Inflammation of the vessel wall prompts transport of excess fluid into the interstitial space and results in the formation of edema (2). Edema located within the vessel wall can be used as a marker for inflammatory activity. Purpose We wished to determine whether edema could be detected in the carotid artery wall by cardiovascular magnetic resonance (CMR) using a T2-weighted shorttau inversion recovery sequence (T2-STIR). Agreement was detected between carotid artery wall enhancement (defined as SI four SD ≥ the sternocleidomastoid muscle) and the uptake of Evans blue (=0.83, p
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
