Detection of communicable and non-communicable diseases using hyperparameter optimization with Bi-LSTM model in pathology images

Abstract

PurposeThe present research work is carried out for determining haemoprotozoan diseases in cattle and breast cancer diseases in humans at early stage. The combination of LeNet and bidirectional long short-term memory (Bi-LSTM) model is used for the classification of heamoprotazoan samples into three classes such as theileriosis, babesiosis and anaplasmosis. Also, BreaKHis dataset image samples are classified into two major classes as malignant and benign. The hyperparameter optimization is used for selecting the prominent features. The main objective of this approach is to overcome the manual identification and classification of samples into different haemoprotozoan diseases in cattle. The traditional laboratory approach of identification is time-consuming and requires human expertise. The proposed methodology will help to identify and classify the heamoprotozoan disease in early stage without much of human involvement.Design/methodology/approachLeNet-based Bi-LSTM model is used for the classification of pathology images into babesiosis, anaplasmosis, theileriosis and breast images classified into malignant or benign. An optimization-based super pixel clustering algorithm is used for segmentation once the normalization of histopathology images is conducted. The edge information in the normalized images is considered for identifying the irregular shape regions of images, which are structurally meaningful. Also, it is compared with another segmentation approach circular Hough Transform (CHT). The CHT is used to separate the nuclei from non-nuclei. The Canny edge detection and gaussian filter is used for extracting the edges before sending to CHT.FindingsThe existing methods such as artificial neural network (ANN), convolution neural network (CNN), recurrent neural network (RNN), LSTM and Bi-LSTM model have been compared with the proposed hyperparameter optimization approach with LeNET and Bi-LSTM. The results obtained by the proposed hyperparameter optimization-Bi-LSTM model showed the accuracy of 98.99% when compared to existing models like Ensemble of Deep Learning Models of 95.29% and Modified ReliefF Algorithm of 95.94%.Originality/valueIn contrast to earlier research done using Modified ReliefF, the suggested LeNet with Bi-LSTM model, there is an improvement in accuracy, precision and F-score significantly. The real time data set is used for the heamoprotozoan disease samples. Also, for anaplasmosis and babesiosis, the second set of datasets were used which are coloured datasets obtained by adding a chemical acetone and stain.