Abstract
Aims: Broad-spectrum carbapenem group is the current therapy for strains of Enterobacteriaceae that express extended spectrum beta-lactamases (ESBLs). However, recent reports of therapeutic failures of carbapenems with strains that produce multiple β-lactamases are being documented. This study profiled antibiotic resistance in clinical isolates of Salmonella species in a tertiary hospital in the Eastern Cape of South Africa with the aim of identifying the status of Salmonella therapy in the region. Study Design: This is an analytical study. Place and Duration of Study: Salmonella isolates (119) from 96 blood and 23 stool specimens of patients attending Nelson Mandela Academic Hospital Complex (NMAHC) and surrounding clinics,
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