Abstract
Background: Autopsy changes in sudden cardiac death due to Acute Myocardial Infarction (MI), is a real challengefor Forensic Pathologist. Immuno-histochemistry has proved significant role in identifying myocardial necrosis.Aim: To find the incidence of deaths due to myocardial ischemia, its changes among the postmortem cases and therole of C9 in identifying deaths due to myocardial infarction by immuno-histochemical staining methods amongautopsy cases.Materials and Methods: Study was conducted on 44 autopsy cases. Multiple tissue samples were collected fromthe heart and other organs, tissue processing and paraffin blocks were made and Hemotoxylin and Eosin (H&E)staining and immuno-histochemical expression was performed for C 9 marker to find out the myocardial necrosis.Data were analyzed using Statistical Package for Social Sciences (SPSS-20) as descriptive statistics.Result: Common age group was 51-60 years. 75% of them were found to have co morbid conditions. Histopathologyfor C9 showed 66% to be positive.Conclusion: Complement C9 factor was used as a reliable marker for identification of early MI in cases which donot show significant histopathological changes with haemotoxylin and Eosin stains.
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