Abstract

This study explores double-walled carbon nanotubes as the sensing devices for biological objects including viruses and bacteria. The biological objects studied include alanine with amino terminal residue, deoxyadenosine with free residue, Coronaviridae and Bartonella bacilliformis. An expression has been articulated to identify the mass of biological objects from the shift of frequency. Sensitivity of the sensor has been calculated when subjected to such biological objects. Molecular structural mechanics approach has been used for investigating the vibrational responses of zigzag and armchair double-walled carbon nanotube-based nano biosensors. The elastic properties of beam element are calculated by considering mechanical characteristics of covalent bonds between the carbon atoms in the hexagonal lattice. Spring elements are used to describe the interlayer interactions between the inner and outer tubes caused due to the van der Waals forces. The mass of each beam element is assumed as point mass at nodes coinciding with carbon atoms at inner and outer wall of DWCNT. Based on the sensitivity and the frequency shift it can be concluded that cantilever zigzag DWCNTs are better candidates for detecting the biological objects.

Highlights

  • In recent times there has been a fast growing interest of carbon nanotubes (CNTs) in biological applications (Tsang et al 1995; Davis et al 1998; Wong et al 1998; Mattson et al 2000) in the field of medicine (Lu et al 2009) and sensing mechanisms (Lin et al 2004; Gu et al 2005) as biosensors

  • This study explores double-walled carbon nanotubes as the sensing devices for biological objects including viruses and bacteria

  • Based on the sensitivity and the frequency shift it can be concluded that cantilever zigzag doublewalled carbon nanotube (DWCNT) are better candidates for detecting the biological objects

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Summary

Introduction

In recent times there has been a fast growing interest of CNTs in biological applications (Tsang et al 1995; Davis et al 1998; Wong et al 1998; Mattson et al 2000) in the field of medicine (Lu et al 2009) and sensing mechanisms (Lin et al 2004; Gu et al 2005) as biosensors. Significant efforts are being made for the use of CNTs as superior biosensor materials, in the light of successful fabrication of various electro analytical nanotube devices, modified by external biological agents (Davis et al 2003; Chen et al 2003; Gooding et al 2003; Li et al 2003). These devices, prepared as single-walled carbon nanotube (SWCNT) transistors, have shown promising sensitivities. Tserpes and Papanikos (2005) presented the atomistic finite element (FE) model of single-walled

Bartonella bacilliformis
Results and discussion
Deoxyadeonosine with free residue
Coronaviridae
Conclusion
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