Detection of anti-rubella IgM, IgG and Antisperm Antibodies in the Sera of Aborted and Non-Pregnant Women in the Kirkuk City

Abstract

Approximately 60% of cases of fetal loss from all repeated abortion conditions are unclear or attributed for some reason.This study was carried out in the Al Kirkuk general Hospital, from August to October 2017. A total of 148 females were screened for anti-sperm antibodies and anti-Rubella antibodies of IgM and IgG type by ELISA, 60 females were undergoing previous abortion(30 Pregnant + 30 Non-pregnant), and control group included 30 pregnant females without previous abortion, and 58 married without pregnancy. The results compared with their corresponding data and statistically analyzed, the revealed the following: The majorities 18(41.8%) of study groups with positive anti-rubella IgG were between the age (26-35) years old, while minority 10(7.1%) frequency of study groups with positive anti-rubella IgG were between the age (36-45) years old. The most of seropositive to anti-rubella IgG are from women whose non-pregnant but with previous abortion20(66.6%), Only 1(3.3%) of pregnant women with previous abortion and pregnant but without previous abortion had seropositive to anti-rubella IgM, while 2(6.6%) in non-pregnantwomenbut with previous abortion. Among these 58 cases about 16 cases was revealed elevated anti-sperm antibody ASA (27.6%). Out of 30 aborted 9 cases were high ASA (30.0%) The sero-prevalence of ASA of study groups according to age groups, just 6 cases of non-pregnant married women (37.6%) of study groups with high ASAwere between the age (25-35) years old, while amongaborted married women5(55.6%) frequency of study groups with high concentration were between the age (25-35) years old. Finally concluding that there is a high rate of susceptibility to rubella infection in women with childbearing age in Kirkuk City. Premarital screening for anti-rubella and vaccination of girls could minimize the risk of infection during pregnancy and childbearing period.ASA may be the cause of infertility in female and may be the cause in the increases of the rate of recurrent spontaneous abortion