Abstract

Hepatitis E virus (HEV) is a zoonotic pathogen commonly considered an important foodborne virus. Pet dogs are important reservoirs of zoonotic agents. In the present study, the seroprevalence of HEV in pet dogs and pet veterinarians were found to be 28.2 and 5.0%, respectively. It remains unclear whether pet veterinarians are at higher risk of HEV transmission. However, pet animals and individuals who have contact with infected animals must be continually monitored for public health concerns.

Highlights

  • Hepatitis E virus (HEV) is commonly considered an important foodborne virus [1]

  • There are four HEV genotypes: genotype-1 and genotype-2 cause the endemic outbreak of hepatitis E in humans in developing countries, whereas genotype-3 and genotype-4 are zoonotic agents associated with sporadic infections in humans, domestic animals, and wild animals worldwide [1, 4]

  • Serum samples obtained from pet dogs were divided into two groups according to the presence of gastroenteritis symptoms, such as diarrhea or vomiting

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Summary

Introduction

Hepatitis E virus (HEV) is commonly considered an important foodborne virus [1]. From a public health perspective, the identification and contamination of HEV in food animals and meat products have been associated with the risk of zoonotic infection and food safety [2, 3]. There are four HEV genotypes: genotype-1 and genotype-2 cause the endemic outbreak of hepatitis E in humans in developing countries, whereas genotype-3 and genotype-4 are zoonotic agents associated with sporadic infections in humans, domestic animals, and wild animals worldwide [1, 4]. Antibodies against HEV were first identified in dogs in India in 2001 [6]. Due to public health issues, pet animals have been eventually considered important reservoirs of zoonotic agents owing to their close contact with humans and

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