Abstract
Attention deficit hyperactivity disorder (ADHD) is a prevalent behavioral, cognitive, neurodevelopmental pediatric disorder. Clinical evaluations, symptom surveys, and neuropsychological assessments are some of the ADHD assessment methods, which are time-consuming processes and have a certain degree of uncertainty. This research investigates an efficient computer-aided technological solution for detecting ADHD from the acquired electroencephalography (EEG) signals based on different nonlinear entropy estimators and an artificial neural network classifier. Features extracted through fuzzy entropy, log energy entropy, permutation entropy, SURE entropy, and Shannon entropy are analyzed for effective discrimination of ADHD subjects from the control group. The experimented results confirm that the proposed techniques can effectively detect and classify ADHD subjects. The permutation entropy gives the highest classification accuracy of 99.82%, sensitivity of 98.21%, and specificity of 98.82%. Also, the potency of different entropy estimators derived from the t-test reflects that the Shannon entropy has a higher P-value (>.001); therefore, it has a limited scope than other entropy estimators for ADHD diagnosis. Furthermore, the considerable variance found from potential features obtained in the frontal polar (FP) and frontal (F) lobes using different entropy estimators under the eyes-closed condition shows that the signals received in these lobes will have more significance in distinguishing ADHD from normal subjects.
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