Detection and real-time analysis of influenza disease using graph data science and a multi-layer perceptron model

Abstract

The influenza virus can spread easily, causing significant public health concern. Despite the existence of different techniques for rapid detection and prevention of influenza, their efficiency varies significantly. Additionally, there is currently a lack of a comprehensive, interoperable, and reusable real-time model for detecting influenza infection and predicting relationships within the field of influenza analysis. This study proposed a comprehensive, real-time model for rapid and early influenza detection using symptoms. Further, new relationships in the influenza field were discovered. Multiple data sources were used for the influenza knowledge graph (KG). Throughout this study, various graph algorithms were utilized to extract significant nodes and relationship features and multiple influenza detection machine learning (ML) models were compared. Node classification and link prediction methods were employed on a multi-layer perceptron (MLP) model. Furthermore, the hyperparameters of the model were automatically tuned. The proposed MLP model demonstrated the lowest rate of loss and the highest specificity, accuracy, recall, precision, and F1-score compared to state-of-the-art ML models. Moreover, the Matthews correlation coefficient was promising. This study shows that graph data science can improve MLP model detection and assist in discovering hidden connections in influenza KG.