Abstract

It is expected that an automatic detection and classification algorithm for the abnormities of first heart sound (S1) can realize computer artificial intelligence diagnosis of some relative cardiovascular disease. Few studies have focused on the detection and classification of the abnormities of S1 and given out in detail the essential differences between abnormal and normal S1. This work applied Empirical Wavelet Transform (EWT) to decompose S1 and extracted the instantaneous frequency (IF) of mitral component (M1) and tricuspid component (T1) by using Hilbert Transform. Firstly, the heart sound signal is preprocessed following these processes: filtering, resampling, normalization and segmentation. Secondly, S1 is decomposed into several modes based on EWT. First two maximal points with a distance greater than 20Hz in Fourier Spectrum of S1 are selected and the nearest minimal points on both sides of the maximal points are found out as the boundaries for segmentation of the spectrum. S1 is decomposed into 5 modes and every mode’s IF are calculated through Hilbert transformation. At last, a k-mean cluster algorithm is applied to cluster the IF of different modes. TD and $A_{peak\_{}ratio}$ are calculated for decision tree classifier and S1s are divided into three categories: normal S1, S1 with abnormal split and S1with abnormal amplitude change. When the proposed method is applied to detect normal S1, Se=94.6%, Pp=98.6% and Oa=93.3%; When it is applied to detect S1 with abnormal split, Se=92.6%, Pp=96.9% and Oa=90%; When it is applied to detect S1 with abnormal amplitude change, Se=94.4%, Pp=95.7% and Oa=90.6%; Comparison experiments are carried out between the proposed method and HVD method. The results show Oa of the proposed method is higher than HVD method when detecting the three different S1s.

Highlights

  • Heart sounds reflect the most primitive mechanical movement of heart

  • To evaluate the performance of proposed method for detection and classification of S1, a wide variety of normal and abnormal heart sound data are taken from some databases, including Michgan Heart sounds Database, 2012 Latest Database and Heart Sounds Database built by 3M littmann

  • The threedimensional scatter diagram of instantaneous frequency (IF) of each mode changing with time and amplitude clearly shows two continuous curves which correspond to the IF of M1 and T1

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Summary

Introduction

Heart sounds reflect the most primitive mechanical movement of heart. With the advent of electronic stethoscope, the real-time storage and playback of phonocardiogram (PCG) are realized [1]. The analysis of heart sound signal can overcome the limitations of human hearing sensitivity and experience, and discover more. The associate editor coordinating the review of this manuscript and approving it for publication was Liangxiu Han. pathological information [2]. It is expected to be a noninvasive, low-cost and convenient diagnostic method through analyzing of heart sound signal [2]–[3]. Many time-frequency analytical methods were applied to analyze various types of heart sounds, but there are few methods to analyze the abnormities of S1. The classical and generally accepted theory for the production of S1 is that it is associated with the closure of the mitral (M1) and tricuspid (T1) valves [4].

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