Abstract

PurposeTo investigate relevant change on the Neck Pain and Disability Scale (NPAD) and Neck Disability Index (NDI) and which questionnaire is the most responsive in patients with non-specific chronic neck pain (CNP).MethodsSeventy-six patients with non-specific CNP in an outpatient tertiary rehabilitation setting were dichotomized into “improved” and “stable” based on global perceived effect (GPE) scores. To investigate relevant change minimal detectable change (MDC) and minimal important change (MIC) with the receiver operator characteristic (ROC) cut-off point were assessed. Comparison of responsiveness was performed using areas under the ROC curve (AUC) and correlations between change scores of NPAD and NDI, and GPE.ResultsMDC and MIC on NPAD (scale 0–100) were 31.7 and 11.5 points, respectively. MDC and MIC on NDI (scale 0–50) were 8.4 and 3.5 points, respectively. Changes should exceed this MDC or MIC cut-off to be interpreted as relevant. AUC was 0.75 for both NPAD and NDI. Correlations between change scores of NPAD and NDI, and GPE were, respectively, 0.48 (95 % CI 0.29–0.64) and 0.49 (95 % CI 0.30–0.64).ConclusionsRelevant change on both NPAD and NDI assessed with MDC and MIC resulted in different cut-offs and consequently with different amounts of certainty that the patient is improved. Responsiveness of NPAD and NDI was similar.

Highlights

  • Correlations between change scores of Neck Pain and Disability Scale (NPAD) and Neck Disability Index (NDI), and global perceived effect (GPE) were, respectively, 0.48 and 0.49. Relevant change on both NPAD and NDI assessed with minimal detectable change (MDC) and minimal important change (MIC) resulted in different cut-offs and with different amounts of certainty that the patient is improved

  • The most frequently used neck disability questionnaires are the Neck Pain and Disability Scale (NPAD) [37] and Neck Disability Index (NDI) [35], which are validated in several languages [4, 16, 21, 22, 38]

  • This study demonstrated that relevant change on both NPAD and NDI assessed with MDC or MIC resulted in different cut-offs with different amounts of certainty that the patient is improved

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Summary

Introduction

The most frequently used neck disability questionnaires are the Neck Pain and Disability Scale (NPAD) [37] and Neck Disability Index (NDI) [35], which are validated in several languages [4, 16, 21, 22, 38]. There is a need to define minimum changes in scores on questionnaires that are relevant from patients-, clinicians- or socioeconomic perspectives [34]. The most commonly used measure is the minimal detectable change (MDC) [3, 5,6,7, 9, 10, 16, 22, 29, 32, 36, 38, 40]. The MDC assesses the minimal magnitude of change required to be confident that the observed change reflects ‘real’ change and not measurement error [1, 8, 10, 30, 34].

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