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Abstract
Variants of severe acute respiratory syndrome coronavirus 2 raise concerns regarding the control of coronavirus disease epidemics. We analyzed 40,000 specific reverse transcription PCR tests performed on positive samples during January 26–February 16, 2021, in France. We found high transmission advantage of variants and more advanced spread than anticipated.
Highlights
Variants of severe acute respiratory syndrome coronavirus 2 raise concerns regarding the control of coronavirus disease epidemics
Assuming that variations in frequencies are driven by transmission advantages, we found that variants have a 50%
We used 2 variant-specific reverse transcription PCR (RT-PCR) tests to detect the fraction of infections caused by SARS-CoV-2
Summary
Variants of severe acute respiratory syndrome coronavirus 2 raise concerns regarding the control of coronavirus disease epidemics. In France, beginning February 5, 2021, every sample that tested SARS-CoV-2–positive by reverse transcription PCR (RT-PCR) underwent an additional variant-specific RT-PCR with probes targeting the Δ69–70 deletion and the N501Y mutation, both in the spike glycoprotein. De) and ID SARS-CoV-2/UK/SA Variant Triplex (ID Solutions, https://www.id-solutions.fr), which target the Δ69–70 deletion and N501Y mutation.
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