Abstract

Efficient real-time detection of epileptic seizures remains a challenging task in clinical practice. In this study, we introduce a new thresholding method to monitor brain activities via a non-uniform multivariate (NUM) embedding of multi-channel electroencephalogram (EEG) signals. Specifically, we present a NUM embedding optimization problem to identify the best embedding parameters. We originate one feature, named non-uniform multivariate multiscale entropy (NUMME), which is extracted from the NUM embedded EEG data. Finally, the extracted feature, compared to an individualized threshold, is used for monitoring and detecting seizure onsets. Experimental results on the real CHB-MIT Scalp EEG database show that our approach achieves a comparable performance to the state-of-art methods. Moreover, it is important to note that we accomplish this without using any sophisticated machine learning algorithms.

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