Abstract

Diabetic Retinopathy (DR) is a disease that causes damage to the blood vessels of the retina, especially in patients having high uncontrolled blood sugar levels, which may lead to complications in the eyes or loss of vision. Thus, early detection of DR is essential to avoid complete blindness. The automatic screenings through computational techniques would eventually help in diagnosing the disease more accurately. The traditional DR detection techniques identify the abnormalities such as microaneurysms, hemorrhages, hard exudates, and soft exudates from the diabetic retinopathy images individually. When these abnormalities occur in combination, it becomes difficult to predict them and the individual detection (traditional 4 class classification) accuracy decreases. Hence, there is a need to have separate combinational classes (16 class classification) that help to classify these abnormalities in a group or one by one. The objective of our work is to develop an automated DR prediction scheme that classifies the abnormalities either individually or in combination in retinal fundus images. The proposed system uses Combined Enhanced Green and Value Planes (CEGVP) for processing the fundus images, Principal Component Analysis (PCA) for feature extraction, and k-nearest neighbor (k-NN) for classification of DR. The suggested technique yields an average accuracy of 97.11 percent using a k-NN classifier. This is the first time that a 16-class classification is initiated that precisely gives the ability and flexibility to map the combinational complexity in a single step. The proposed method can assist ophthalmologists in efficiently detecting the abnormalities and starting the diagnosis on time.

Highlights

  • Diabetes is an epidemic affecting millions of people worldwide [1]

  • Microaneurysms are the hallmark of Non-Proliferative Diabetic Retinopathy (NPDR) [7]

  • The proposed method achieved the highest accuracy compared to all the similar methods that use k-nearest neighbor (k-NN) or SVM classifiers

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Summary

INTRODUCTION

Diabetes is an epidemic affecting millions of people worldwide [1]. DR is a chronic retinal disorder that is caused by the long-term impact of diabetes mellitus [2]. People with diabetes and less controlled blood sugar are likely to suffer from DR It occurs when high blood sugar levels damage the walls of small blood vessels in the retina [3]. In DR, blood vessels leak fluid and blood on the retina These vessels form features such as microaneurysms, hemorrhages, hard exudates, and soft exudates or cotton-wool spots [5]. Hard exudates are an ophthalmoscopic feature of background diabetic retinopathy [8] They result from an increase in vascular permeability and the leakage of fluid and lipoprotein in the surrounding tissue. The hard exudates are fat-filled (lipoidal) histiocytes They are small white or yellowish-white deposits with sharp margins in the outer layers of the retina, deep in the retinal vessels.

LITERATURE REVIEW
METHODOLOGY
Background removal
AND DISCUSSION
Result Analysis
Discussions
Findings
CONCLUSION

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