Abstract
Dengue fever is a zoonosis maintained in nature by mosquitoes transmitting virus between non-human primate species, most of which develop clinically i n apparent infection. It has been found to be endem ic in Africa and beyond. A survey for Dengue virus IgM antibody was carried out in Ogbomoso (urban and rural areas) using Enzyme Linked Immunosorbent Assay ( WKEA Med Supplies Corp , Dengue fever virus ELISA Kit (China ),) to determine the seroprevalence and true incide nce of dengue virus in Ogbomoso. A total of 186 apparently healthy individuals were recruited i nto the study. The sera of 93 subjects who consente d to participate were collected. The mean age of the sub jects tested was 37.6±0.67. Anti-Dengue virus IgM antibodies were found in 16/93, (17.2%). The highes t prevalence of anti-Dengue 28.6% was found in persons whose ages were between 0-15 years, males (18.9%), civil servants (26.3%) and urban dwellers (21.3%). The findings from this study show that the re is primary infection of this virus in Ogbomoso a nd suggest the need for preventive and control measure s against dengue fever virus.
Highlights
Dengue fever is aglobally significant arthropod-borne virus seems to have no detrimental effect on the viral disease infecting people annually
Dengue has been reported in many parts of subSaharan Africa; it is underreported and under recognized in malaria endemic regions because greater than 70% of febrile illnesses are treated presumptively as malaria
Different studies have shown that dengue virus is actively circulating in various parts of Nigeria (Dawurung et al, 2010; Baba and Talle, 2011)
Summary
Dengue fever is aglobally significant arthropod-borne virus seems to have no detrimental effect on the viral disease infecting people annually. Dengue fever virus is primarily transmitted by Aedesaegypti (Weaver and Reisen, 2010). Dengue fever virus is maintained in nature in cycles that involve preferred blood-sucking vectors and vertebrate hosts (Gulber, 2010), the virus is maintained in the forests of Southeast Asia and Africa by transmission from female Aedes mosquitoes-of species other than Aedesaegypti-to her offspring and to lower mosquitoes transmitting virus between non-human primate species, most of which develop clinically inapparent infection. Dengue virus has been shown to be actively circulating in various parts of Nigeria (Dawurung et al, 2010; Baba and Talle, 2011). Dengue is an acute viral illness with clinical fever virus in Ogbomoso.
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