Detailed overview on pharmaceutical dosage forms in treatment of acne

Abstract

Acne vulgaris is a skin condition characterized by an obstruction or inflammation of the oil glands, present on skin's surface, which are collectively termed as pilosebaceous units. The skin on face, back, and upper chest have a greater number of sebaceous follicles. Topical, systemic, or combination therapy can be used to treat acne, while mild and moderate acne are generally treated with topical therapy. Topical acne therapy has direct access to the target site (skin) prior to reaching the blood stream, thereby reducing the systemic adverse effects of delivery of drug via parenteral or oral routes. Oral antibiotics, on the other hand, are a crucial treatment for acne which have not improved with topical treatment and for inflammatory lesions, such as pustules, nodules, and papules. Due to their capability to improve dermal therapeutics by boosting therapeutic efficacy and lowering adverse effects, nanodelivery technologies, developed to address skin delivery difficulties, have been extensively investigated. The goal of this study is to go through the many types of pharmacological dosage forms that are available for the treatment of acne.