Abstract
A 51-year-old lady presented with a sudden, painless blurring of vision in the left eye. She was on oral antidepressant desvenlafaxine, a serotonin-norepinephrine reuptake inhibitor, for the past 3 years. Her visual acuity was 6/6 OU. Fundus examination of the left eye revealed opacification of the retina as a result of retinal arterial occlusion. Nasal as well as temporal retinal quadrants were involved. Inferior half of the macula was also affected. Fundus fluorescein angiography of the left eye was unremarkable while spectral domain optical coherence tomography of the macula showed microcystic changes. After excluding embolic and nonembolic causes, we hereby report a case of retinal arterial occlusion resulting from desvenlafaxine-associated transient retinal arterial vasospasm, for the first time.
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