Abstract
Desmoplastic ameloblastoma is a variant of ameloblastoma first described in 1984. The histopathologic features of 60 ameloblastomas diagnosed at Taichung Veterans General Hospital during years 1982-2001 were reviewed with special reference to the incidence of the desmoplastic variant. Only two cases fulfilled the criteria of a desmoplastic ameloblastoma, representing 3.3% (2/60) of all the intraosseous ameloblastomas. One of the rumor occurred in the mandible and the other located in the maxilla. Both cases contained abundant coarse collagenous stroma, and scattered islands and nests of atypical odontogenic epithelium with a surrounding acellular or hyalinized zone. Stellate cells within the central area of some of the neoplastic cell nests were observed. Radiographically, both cases exhibited a mixed radiolucent/radiopaque appearance with poorly defined borders, suggestive of fibro-osseous lesions. The clinical, radiographic, ad microscopic aspects of this unusual lesion are presented, and the relevant literature is reviewed.
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