Desmoid-Aggressive Fibromatosis

Abstract

Following surgical excision alone, local recurrences occur in 27–57 percent of cases of desmoid — aggressive fibromatosis. Radiation therapy in doses of 5000–6000 rad decreases local recurrence rates. Normal tissue tolerance may be limiting for the total dose of external beam radiation; therefore either post-operative brachytherapy or brachytherapy following external beam may be used. Regression rates may occur from eight months to two years following treatment. Desmoid — aggressive fibromatosis may occur in association with Gardner’s syndrome and pregnancy. A seventy percent local control rate has been reported with external radiation. In the national survey eighty-two percent of radiation oncologists would treat desmoid — aggressive fibromatosis.KeywordsDesmoid TumorCystic HygromaAggressive FibromatosisNormal Tissue ToleranceRoentgen TherapyThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.