Abstract
Objective: To analyze the effect of the characteristics of the donor and the preparation of donor graft in the success of Descemet's membrane endothelial keratoplasty (DMEK). Material and Methods: The patient and donor charts and the surgical videos of the cases that underwent DMEK between June 2017 and June 2020 were analyzed. Age, gender, diagnosis, Descemet's membrane (DM) attachment at the postoperative first week and the last visit from the patients' charts and age, gender, systemic diseases, and drugs from the donors' charts. The cases were divided into 2 groups; the cases with DM detachment (Group 1) and attached DM (Group 2) at the postoperative first week. Results: Fifty-three DMEK surgeries from 53 recipients with 53 DM grafts from 41 donors were analyzed. On the first postoperative week, DM was detached in 8 (15.1%, Group 1) cases and attached in 45 (84.9%, Group 2) cases. There were no statistically significant differences in the characteristics of the recipient or donor between groups. However, the amlodipine and doxazosin use of donors were found to be significantly higher in Group 1 (p=0.041, p=0.011; respectively). Conclusion: DM grafts may be used, regardless of the characteristics of the donor, in DMEK to compensate for the shortage of donors.
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