Abstract

BackgroundRetina degenerative disorders represent the primary cause of blindness in UK and in the developed world. In particular, Age Related Macular Degeneration (AMD) and Retina Pigmentosa (RP) diseases are of interest to this study. We have therefore created new image processing algorithms for enhancing the visual scenes for them.MethodsIn this paper we present three novel image enhancement techniques aimed at enhancing the remaining visual information for patients suffering from retina dystrophies. Currently, the only effective way to test novel technology for visual enhancement is to undergo testing on large numbers of patients. To test our techniques, we have therefore built a retinal image processing model and compared the results to data from patient testing. In particular we focus on the ability of our image processing techniques to achieve improved face detection and enhanced edge perception.ResultsResults from our model are compared to actual data obtained from testing the performance of these algorithms on 27 patients with an average visual acuity of 0.63 and an average contrast sensitivity of 1.22. Results show that Tinted Reduced Outlined Nature (TRON) and Edge Overlaying algorithms are most beneficial for dynamic scenes such as motion detection. Image Cartoonization was most beneficial for spatial feature detection such as face detection. Patient's stated that they would most like to see Cartoonized images for use in daily life.ConclusionsResults obtained from our retinal model and from patients show that there is potential for these image processing techniques to improve visual function amongst the visually impaired community. In addition our methodology using face detection and efficiency of perceived edges in determining potential benefit derived from different image enhancement algorithms could also prove to be useful in quantitatively assessing algorithms in future studies.

Highlights

  • Retina degenerative disorders represent the primary cause of blindness in UK and in the developed world

  • In this article we have described three different image enhancement algorithms developed for patients suffering from retinal degenerative diseases

  • The image processing model allows us to reconstruct the information stream towards the visual cortex and assess our algorithms using objective tests such as face detection. Results from this model show that Tinted Reduced Outlined Nature (TRON) and edge overlaying algorithms are very useful in detecting spatial features in dynamic scenes and perceiving the edges of simple objects in static scenes

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Summary

Introduction

Retina degenerative disorders represent the primary cause of blindness in UK and in the developed world. Age Related Macular Degeneration (AMD) and Retina Pigmentosa (RP) diseases are of interest to this study. There are 110 million people who have severely impaired vision. The low vision pathologies of this latter group can be divided mainly into two categories; those that predominantly suffer from a loss of visual acuity due to macular degenerations, and those that predominantly suffer from a reduction in the overall visual field such as Retinitis Pigmentosa. Despite advances in treatment such as antivascular endothelial growth factor agents for exudative age related macular degeneration (wet-AMD) and medical and surgical management of glaucoma, there are still a significant number of conditions which lead to severe sight loss. Dry AMD, and untreatable diabetic retinopathy, as well as inherited retinal degenerations such as Retinitis Pigmentosa (RP) are significant examples of these [3]

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