Abstract
A unique library of amide functionality carrying bis-1,3,4-oxadiazole-oxazolo[4,5-b]pyridin-2-yl) derivatives (10a-j) with proven chemical structures has been synthesised. They were tested for preliminary anticancer properties against various human cancer cell lines such as human prostate cancer (PC3), human lung cancer (A549), human breast cancer (MCF-7) and human colon cancer (Colo-205) using the MTT assay and chemotherapeutic agents such as etoposide as the reference drug. When compared to etoposide, all drugs shown greater efficacy against all cell lines.
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